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欧盟评估一种3-植酸酶作为家禽、育肥猪和小型猪种饲料添加剂的安全性和有效性

2022-11-11 15:59:04        来源:食品伙伴网


(资料图片)

    2022年11月9日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就一种3-植酸酶(3-phytase)作为家禽、育肥猪和小型猪种饲料添加剂的安全性和有效性发表科学意见。

据了解,这种3-植酸酶由Komagataella phaffii (CECT 13171) (FSF10000/FLF1000) 产生。经过评估,专家小组无法就添加剂对目标物种、消费者、使用者和环境的安全性做出结论。该添加剂在500 FTU/千克饲料的剂量下,对育肥或饲养用于产蛋/繁殖的家禽品种、育肥猪和小型猪种是有效的,在1000 FTU/千克饲料的剂量下,对产蛋鸡是有效的。部分原文报道如下:

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 3-phytase produced by Komagataella phaffii (CECT 13171) (FSF10000/FLF1000) as a zootechnical additive for poultry species, pigs for fattening and minor porcine species. The production strain (CECT 13171) is genetically modified and was developed from a strain that had been previously assessed by the FEEDAP Panel. The genetic modifications present in K. phaffii CECT 13171 do not raise safety concerns and no recombinant DNA was detected in the final formulations of the additive (FSF10000/FLF1000). However, the Panel could not conclude on the identity of the production strain and uncertainty remained on the possible presence of viable cells of the production strain in the final formulations. Owing to these uncertainties, the FEEDAP Panel could not conclude on the safety of the additive regarding the production strain. The additive in either form is not irritant to eyes and skin, the liquid formulation is not a dermal sensitiser but the solid formulation is, and the two formulations should be considered potential respiratory sensitisers. The FEEDAP Panel concluded that the 3-phytase present in the additive is safe for the target species at a level of 1,000 FTU/kg feed and that would not raise safety concerns for the environment. However, considering the uncertainties on the identification of the production strain and the possible presence of viable cells in the final formulations, the Panel could not conclude on the safety of the additive for the target species, consumer, users, and the environment. The FEEDAP Panel concluded that the additive is efficacious at 500 FTU/kg feed in poultry species for fattening or reared for laying/breeding, pigs for fattening and minor porcine species and at 1,000 FTU/kg feed in laying hens.

关键词: 饲料添加剂

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