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世界观天下!欧盟评估一种2′-岩藻糖基乳糖作为新型食品的安全性

2022-12-16 11:20:37        来源:食品伙伴网


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    2022年12月14日,据欧盟食品安全局(EFSA)消息,欧盟营养、新型食品和食物过敏源(NDA)研究小组就一种2′-岩藻糖基乳糖(2′-fucosyllactose)作为新型食品的安全性发表科学意见。

据了解,该2′-岩藻糖基乳糖是由谷氨酸棒杆菌ATCC 13032的衍生菌株生产的。经过评估,专家小组得出结论,在提议的使用条件下,2′-岩藻糖基乳糖作为新型食品是安全的。部分原文报道如下:

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2′-fucosyllactose (2’-FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human-identical milk oligosaccharide (HiMO) 2’-FL, but it also contains d-lactose, l-fucose, 3-fucosyllactose, difucosyllactose, d-glucose and d-galactose. The NF is produced by fermentation with a genetically modified strain (APC199) of Corynebacterium glutamicum ATCC 13032. 2’-FL, when chemically synthesised or produced by fermentation with derivative strains of Escherichia coli K-12 DH1 or E. coli BL21 (DE3), is already authorised and included in the EU list of NFs. This application refers to a change in the production process and specifications, while target population, conditions of use and consequently, the anticipated intake remain unchanged. The information provided on the identity, production process, composition and specifications of the NF does not raise safety concerns. The intake of other carbohydrate-type compounds structurally related to 2’-FL is also considered of no safety concern. In line with other milk oligosaccharides that are natural components of human milk, the safety assessment of this NF is mainly based on the comparison between the intake of breastfed infants and the estimated intake as NF. Given that the NF would be consumed at the same extent as the already authorised 2’-FL, the Panel considers that the consumption of the NF at the proposed uses and use levels does not raise safety concerns. The Panel concludes that the NF is safe under the proposed conditions of use.

关键词: 岩藻糖基乳糖

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